Knowing when to start amazon kindle ebook publishing depends on how ready your manuscript is, not just your idea. You should begin once your book is properly edited and formatted to meet Kindle standards. Many authors choose to start amazon kindle ebook publishing when they have a clear cover design and a strong book description ready. It is also best to publish when you can plan a simple marketing strategy to reach early readers. Overall, the right time for amazon kindle ebook publishing is when your book is polished and you are confident to present it to the world.