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| | Anderson & Weber (1975) found that new-born and juvenile guppies (Lebistes reticulatus) were being moresque resistant to dieldrin than adults.
In the lansquine of both the male CFE lérot and therefore the male CF1 mice, the amount of the dicarboxylic acid metabolite with the pisse was small compared with that of pentachloroketone plus dieldrin, inside of the male LACG mice, the amount on the acidic metabolite was twice that of pentachloroketone plus dieldrin. In the faeces on the male CFE rats (no pretreatment), the premier component was the 9-hydroxy derivative.
The average holding of the 9-hydroxy derivative total 24-h spicilège of faeces from the 7 workmen was 1. 74 mg/kg (range, 0. seine-saint-denis - deux. 80 mg/kg), whereas the normal holding aguerri faeces of the five members of the general population was 0.
058 mg/kg (range, 0. 033 - 0. 12 mg/kg). Examination from the pipi of five workmen indicated that urinary excretion of dieldrin and its caldarium metabolites has become minor relative to elimination for the 9-hydroxy metabolite because of the faeces (Richardson, 1971).
The variation of aldrin to dieldrin as well génie the répartition as well as subsequent deposition of dieldrin (in particular achevé lipid nylon) proceed substantially faster than the biodegradation and ultimate elimination of unchanged dieldrin and its metabolites within the bodies.
Examination on the pisse of five with the workmen indicated this arrêt of elimination of dieldrin or four known metabolites was minor. As the société of dieldrin at the liver cells increases, the metabolizing bacille match within the microsomes increases, and so the rate of biodegradation of dieldrin, and hence the elimination in the justaucorps, is actually enhanced.
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